Hydroxyapatite (HA) is an essential element required for bone regeneration. Different forms of HA have been used for a long time. The essence of bone regeneration always revolves around the healthy underlying bone or it may be the surroundings that give enough strength. HA is well known for bone regeneration through conduction or by acting as a scaffold for filling of defects from ancient times, but emerging trends of osteoinductive property of HA are much promising for new bone regenerationHA is one of the bioceramics that represents the large quantity of regenerative graft material available in the market. HA is very closely associated with the bony apatite structure. It is one of the inorganic components of the bone. It is bounded in the organic matrix, so that it exists with other mineral trace elements in the normal bone.